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KMID : 0043320080310111477
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Archives of Pharmacal Research
2008 Volume.31 No. 11 p.1477 ~ p.1482
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New Phenylpropanoid Esters of Sucrose from Polygonum hydropiper and Their Antioxidant Activity
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Kim Young-Ho
Minh Chua Van
Huong Le Mai
Huong Thanh
Hoa Tran Quynh
Cuong Nguyen Xuan
Nhiem Nguyen Xuan
Kiem Phan Van
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Abstract
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By various chromatographic methods, two new phenylpropanoid esters of sucrose named hidropiperosides A (1) and B (2), and three known compounds as vanicosides A (3), B (4), and E (5) were isolated from the methanolic extract of the whole plant of Polygonum hydropiper L. (Polygonaceae). Their structures were elucidated by extensive spectroscopic methods including 1D- and 2D-NMR experiments, as well as ESI-MS analysis. All the isolated compounds were tested for their antioxidant activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay system. Among them, compounds 2 and 3 showed significant antioxidant activity with their SC50 values of 23.4 and 26.7 μg/mL, respectively.
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KEYWORD
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Polygonum hydropiper, Polygonaceae, Hidropiperoside A, Hidropiperoside B, Antioxidant
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